Biography:

The head of Institute for the Nuclear Medicine, Military Medical Academy, Belgrade. Prof. Dr Sc. Med of Nuclear Medicine. Born in Vrginmost, Croatia, February 1st, 1954. Graduated from the University of Belgrade in 1978, Nuclear Medicine specialization in 1984, and in London in 1987. He defends his doctoral thesis in the field of nuclear medicine in 1996. Instructor of Nuclear Medicine for Students Specializing in Internal Medicine and Surgery from 1985. Since 2004. the head of The Institute for the Nuclear Medicine, Military Medical Academy; since 2011. the head of The Group of Diagnostic Institutes at the Military Medical Academy; since 2012. professor in The Medical School of the Military Medical Academy for the course Nuclear Medicine; 2013. tenured professor for the course Nuclear Medicine. Has over 250 specialized and scientific published articles, in domestic and foreign journals, chapters in books: “The Lung Tumors,” 2000, and “Tc Generators,” 2003; author of the chapter in the textbook for the Medical School in the University of Thessaloniki, 2014; Ajdinović, B. at al., “Normal and pathological parathyroid glands,” Medical College, Belgrade, 2004; Ajdinović, B. at al, “Child with an urinary tract infection,” Belgrade, 2008; Ajdinović, B. at al, “Nuclear medicine - Textbook for students in The Medical School of the Military Medical Academy,” Belgrade, 2015. In charge of the nuclear medical research on kidneys in 1987, and, in 2006, of the research about the urinary tract infection in children; participates in the international project “Variability in DMS scintigraphy findings,” in 2007. From 2011 to 2014, participates in the project “Cellular and molecular pathogenetic mechanisms in disorders of reproduction and genital organs - prevention, diagnostics, and therapy” - subproject: “Treatment of antenatal hydronephrosis” of the Ministry of Science and Technological development; from 2011 to 2015, in charge of the project: Nuclear medical research of urinary tract in children: antenatal hydronephrosis, infection of urinary tract in children, and vesicoureteral reflux as causes of renal parenchymal disease. In 2001, awarded The Medal of White Angel from the president of the SR Yugoslavia; in 2008, “Author of the year” by the Military Sanitation Examination magazine; in 2011, awarded third prize at the first Medicinal Olympics in Thessaloniki, and in 2015, the first prize at the third Medicinal Olympics in Thessaloniki. Member of the World Association of Radiopharmacological and Molecular Therapy of the European Society of Nuclear Medicine, Serbian Medical Society, and the Society of Nuclear Medicine of Serbia

Abstract:

Obstructive uropathy can be defined as any blockage of urine drainage from the kidney (renal calyces or renal pelvis), ureter, or bladder. As a result of the blockage, urine backs up into the kidneys, causing dilatation of the ureter, renal pelvis, and renal calyces, which can damage the kidney if it is not treated. The appearance of dilated or enlarged renal pelvis and calyces is referred to as hydronephrosis and is a sign of obstructive uropathy

There are many causes of obstructive uropathy; however, the most common causes include stones in kidneys (nephrolithiasis), ureter (ureterolithiasis) or anywhere in the urinary tract (urolithiasis). Other causes of obstructive uropathy include health conditions such as pregnancy, prostate cancer, retroperitoneal fibrosis, spinal cord injury, ureteral stricture, and congenital anomalies (e.g., ureteropelvic junction obstruction [UJO]), which is most common in children but also occurs in adults. The gold standard to assess urinary obstruction is unclear; therefore, several imaging modalities are often used. Helical CT (especially without contrast) rapidly is replacing kidneys-ureters-bladder  x-rays as the first step in the radiologic evaluation of the urinary system, MRI, where available, is becoming the imaging study of choice for urinary obstruction. IV pyelography (IVP)  is the procedure of choice for defining the extent and anatomy of obstruction.  Invasive pyelography provides the same information as IVP without depending on renal function and can be used when the risks of IVP are considered too great. Ultrasonography is the procedure of choice for determining the presence of hydronephrosis.  Other possible methods could include the Whitaker test, which is invasive and has been largely replaced by CT. Diuretic dynamic scintigraphy (renography) has been adopted as a noninvasive clinical management tool to assist in differentiation  the various causes of hydronephrosis from that of obstruction.

Biography:

Abstract: